Medusa Netflix Series: Cast, Plot, and Trailer of the Thriller - Netflix Tudum

  • Deep Dive

    Who’s in the Cast of Medusa? Everything to Know About the Thriller

    The Spanish series about a CEO assassination attempt stars Juana Acosta and Manolo Cardona.

    By Ingrid Ostby
    March 7, 2025

When a newly minted CEO miraculously survives after her yacht explodes off the coast of Colombia, she teams up with a dogged detective to find out who tried to kill her. As their investigation deepens, her family’s dark secrets are unearthed. The Colombian drama thriller Medusa, co-created by Said Chamie and Claudia Sánchez (The Queen of Flow), stars Juana Acosta, Manolo Cardona, Laura Archbold, Sebastián Martínez, and Adriana Arango.

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When will Medusa be released?

Stream it now.

Where can I find the trailer for Medusa?

Check it out at the top of this page. 

A man wearing a green tank top with a bloodied face stands in front of Manolo Cardona as Danger in a police interrogation room in an image from the series ‘Medusa.’

Who’s in the cast of Medusa?

  • Juana Acosta (The Innocent) as Bárbara Hidalgo
  • Manolo Cardona (Who Killed Sara?) as Detective Danger Carmelo
  • Sebastián Martínez (The Accident) as Esteban Arco, Bárbara’s husband and the purchasing director
  • Adriana Arango (The Queen of Flow) as Jacqueline Hidalgo, aka Jackie, Camilo’s wife and vice president of nonprofit foundations
  • Luis Fernando Hoyos (Always a Witch) as Uncle Camilo, vice president of imports, exports, harbors, and merchant fleet, Bárbara’s uncle
  • Juanita Molina (Miss Adrenaline: A Tale of Twins) as Viviana, Úrsula’s stepdaughter and Bárbara’s half-sister
  • Mabel Moreno (The Queen of Flow) as Úrsula, Bárbara’s stepmother
  • Mariana Mozo (Dejémonos de Vargas) as Maya, Bárbara’s daughter
  • Sebastián Osorio (Pasión de Gavilanes) as Jacobo Hidalgo, Bárbara’s cousin and the sporting deputy director of all divisions of the Babilla Baseball Club
  • Carlos Torres (Dark Desire) as Cristian Hidalgo, who becomes Medusa’s CEO after Bárbara goes missing
  • Diego Trujillo (Griselda) as Damián, Bárbara’s father
  • Laura Archbold (Imposters) as Tatiana
  • Ramsés Ramos (Alias J.J.) as Coronel Giraldo
  • Johan Rivera (The Great Heist) as Porras
  • Ángela Rodríguez (Los Billis) as Eluney
  • Biassini Segura (Don’t Blame the Kid) as Gabriel
  • Jacqueline Arenal (The Marked Heart) as Esperanza
  • Jair Romero (Love of My Life) as Ramiro
  • Isabel Gaona (All for Love) as Madrina Eluney
  • Lucas Buelvas (Enfermeras) as Diego
  • Diana Wiswell (Leading Ladies) as Clara
  • Felipe Botero (Primate) as Saúl

What happens in Medusa?

Millionaire Bárbara Hidalgo was just crowned CEO of her family’s powerful business conglomerate, Medusa, which has a near monopoly on Colombia’s northern coast. While out sailing solo on her luxury yacht before her new gig commences, she nearly loses her life: The yacht explodes, and Bárbara’s thrown into the water. Everyone assumes she’s dead — except for Detective Danger Carmelo, who’s convinced the Hidalgos are withholding information that’s crucial to his missing person investigation. And he’s right — Bárbara washes up seemingly unscathed. But is she really the same person as she was before the accident? And who’s behind this failed assassination attempt? As a tangled web of family secrets emerges, Bárbara must confront who she really is — and why her own flesh and blood wants her dead. 

In an image from the series ‘Medusa,’ Carlos Torres as Cristian and Juana Acosta as Bárbara Hidalgo sit outside with a sunset ocean view at their backs.

Is Medusa based on a book?

No, it’s an original story. 

In an image from the series ‘Medusa,’ Juana Acosta as Bárbara Hidalgo looks out of a building onto a blurred man sitting in his car.

Is Medusa based on a true story?

No, it’s fictional. 

Where does Medusa take place?

The series takes place in Barranquilla, Colombia. 

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